《植物生理学报》 2012, 48(7): 643-653

Whirly转录因子研究进展

孔凡英, 邓永胜, 周斌, 孟庆伟*

山东农业大学生命科学学院, 作物生物学国家重点实验室, 山东泰安271018

通信作者：孟庆伟；E-mail: qwmeng@sdau.edu.cn；Tel: 0538-8249606

摘　要：

Whirly蛋白是广泛存在于植物细胞内的一种转录因子。它既能与单链DNA结合, 也能与RNA结合, 无论在细胞核还 是在质体内都有着广泛而复杂的生物学功能。本文概述了Whirly蛋白的结构、种类、分布及其作用机制, 并重点讨论了 其在细胞核及质体内的功能, 最后对Whirly蛋白研究中需要解决的问题做了展望。

关键词：转录因子; Whirly蛋白; 单链DNA结合蛋白

收稿：2012-04-19   修定：2012-05-24

资助：国家重点基础研究发展计划(2009CB118505)和国家自然科 学基金(31071338, 31171474)。

Research Advancement of Whirly Transcription Factors

KONG Fan-Ying, DENG Yong-Sheng, ZHOU Bin, MENG Qing-Wei*

State Key Laboratory of Crop Biology, College of Life Sciences, Shandong Agricultural University, Tai’an, Shandong 271018, China

Corresponding author: MENG Qing-Wei; E-mail: qwmeng@sdau.edu.cn; Tel: 0538-8249606

Abstract:

Whirly transcription factors which are ubiquitous in the cell were shown to bind to both ssDNA and RNA and have different functions both in nucleolus and plastids. This review summarizes the crystal structure, distribution, mechanism of Whirly proteins binding to ssDNA and focuses on their functions in nucleolus and plastids. The problems remain to be determined are also prospected.

Key words: transcription factor; Whirly protein; single-strand DNA binding protein